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Clinical trials for Ovary

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BGOG-ov62/N-Plus

Trial drug
Niraparib
Histology
Serous, Endometrioid Clear-cell
Grade
High grade
Prior lines
Frontline
Phase
II
Biomarkers
HRD
Open

BGOG-ov63/NIRVANA-1

Trial drug
Bevacizumab, niraparib
Histology
Serous, Endometrioid
Grade
High grade
Prior lines
Frontline
Phase
II
Open

BGOG-ov81/VS-6766-301

Trial drug
Avutometinib, Defactinib
Histology
Serous
Grade
Low grade
Platin
Platinum sensitive
Platinum resistant
Secondary platinum refractory
Prior lines
1, 2, 3, 4, >4
Phase
III
Open

REGN5668

Trial drug
REGN5668, REGN4018, Cemiplimab
Histology
Serous, Endometrioid Clear-cell Mucinous Other (bv. mixed/rare)
Grade
High grade, Low grade
Platin
Platinum sensitive
Platinum resistant
Primary platinum refractory
Secondary platinum refractory
Prior lines
1, 2, 3, 4
Phase
1/2
Open

REGN4018

Trial drug
REGN4018, Cemiplimab
Histology
Serous, Endometrioid Clear-cell Mucinous Other (bv. mixed/rare)
Grade
High grade, Low grade
Platin
Platinum sensitive
Platinum resistant
Primary platinum refractory
Secondary platinum refractory
Prior lines
1, 2, 3, 4
Phase
1/2
Open

BGOG-ov80/ALEPRO

Trial drug
Abemaciclib, Letrozole
Histology
Serous, Endometrioid Other (bv. mixed/rare)
Grade
Low grade
Platin
Platinum sensitive
Platinum resistant
Prior lines
1, 2, 3, 4, >4
Phase
II
Open

BGOG-ov76/GLORIOSA

Trial drug
Mirvetuximab soravtansin, Bevacizumab
Histology
Serous
Grade
High grade
Platin
Platinum sensitive
Prior lines
1
Phase
III
Biomarkers
⍺FR
Open

REJOICE/DS6000-126

Trial drug
Raludotatug Deruxtecan (R-DXd)
Histology
Serous, Mucinous Endometrioid Clear-cell
Grade
Low grade
Platin
Platinum sensitive
Platinum resistant
Primary platinum refractory
Secondary platinum refractory
Prior lines
1, 2, 3, 4, >4
Phase
II
1
2 3
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